There are just some people who don't want others to be kind to them. Expressing some care and concern...well, it's almost like it's offensive to them. They project their feelings about their heartache onto you, making you the object of anger. The more you care...the more gasoline you throw on a fire that's set to burn you.
And I have to admit...it's a weird feeling. Being the irritant because of attempts to love...
How to respond?
Hard to say.
You could make them less uncomfortable by not caring. I guess you'd save yourself the grief...well, grief of one kind. You could continue, knowing you'll get treated badly...maybe for a good cause? A consequence well worth it? You could grab onto them and hold them...escalate but abbreviate?
Woo! What a tough one.